口 1.The film director was terribly __ by the negative responses from the audience.-|||-A.frustrated-|||-B.interrupted-|||-C.bothered-|||-D.

步骤 1：理解题意
题目的意思是：这部电影的导演被来自观众的负面评价严重打击了。
步骤 2：分析选项
A. frustrated 沮丧、受挫折
B. interrupted 打断(讲话等)
C. bothered 打扰，烦恼
D. prevented 阻止
步骤 3：选择正确答案
根据题意，导演被负面评价打击，因此选择表示“沮丧、受挫折”的选项A。